It is difficult to know exactly when the shift from gelatine to agar occurred. As often happens for scientific breakthroughs, agar was likely adopted incrementally alongside the use of other growth media. In 1913, for example, the first diagnosis of Serratia marcescens as a human pathogen was made by growing it on agar as well as on potatoes.
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On top of Kudrow and Bucatinsky, The Comeback Season 3 will see the return of many familiar faces, including Damian Young as Valerie's husband Mark Berman and Laura Silverman as reality TV director Jane Benson.
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Netflix, Amazon, and Apple are reportedly interested in buying Warner Bros.